Familial Early-Onset Parkinsonism, Unique Features and Socioeconomic Impact- ACase Report with Literature Review

Abstract

Early-onset Parkinson's disease (EOPD) is rarer than the classical late-onset Parkinson's disease (LOPD). It refers to subjects with onset of symptoms between 21 and 40 or 50years of age. It progresses at a slower rate than LOPD, however has a greater impact on family, professional and social life as it occurs at the prime of life. A genetic aetiology is believed to be more common in EOPD than in LOPD. We present a 34year old right-handed primary school female teacher with onset of features of Parkinsonism at the age of 28years. There was family history of similar symptoms in father and paternal step-brother whose symptoms started in their early forties and early thirties respectfully. A correct diagnosis of EOPD is essential to aid management which usually involves a multi-disciplinary approach.